Only child Julia Bechley finds her life turned-upside down when her father reveals that, over the course of his prize-winning career as a pioneering fertility doctor, he used his own genetic material to conceive upwards of dozens of children. Reeling from this explosive revelation, Julia discovers two new sisters - former best friend Edie Palmer and ex-Olympic athlete Roxy Doyle.
As these three young women begin to embrace their new reality, Julia must figure out what life is like without her father by her side; Edie comes to grips with her burgeoning sexuality, as her marriage falters; and Roxy faces adulthood out of the spotlight.
Against all odds, the three women will attempt to form a bond as sisters, even as they must welcome a tidal wave of new siblings into their rapidly expanding family.
- Brittany Snow as Julia Bechley
- Megalyn Echikunwoke as Edie Palmer
- Emily Osment as Roxy Doyle
- Timothy Hutton as Leon Bechley
- Mo McRae as Tim Moore
- Mustafa Elzein as Isaac Abadi
- Victoria Cartagena as Amanda Doherty
- Chris Conroy as Sam
- Marcia DeBonis as Jan
- Andrew Pang as Michael Cheng
- Carme Boixadera as Kim
- Maggie Weston as Jane Horner
- Julie Potter as "Former Patient"
- Philip Hernandez as "Attorney"
- Kevin Michael Murphy as "Creepy Guy"
- Jamar Greene as Alex Bonilla
- Kathleen Kwan as "Female Nurse"
- Carleigh Bettiol as "Event Planner"
- Akeda Abrams as Officer Balter
- Madeleine Bundy as "Legal Assistant"
- Amanda Barron as "Therapist"
- Sebastian Prandoni as Cobie
- Sally Mayes as "Older Woman"
- Dorothy Meyers as "Desk Jockey"
- Delphine Talty as "Female Fan #1"
- Heaven Michelle McCoy as "Female Fan #2"
- Emily Hsu as "Reporter #2"
- Kevin Sebastian as "Reporter #3"
- Johnny Castro as "Former Patient"
- Andreas Pliatsikas as "Gala Guest"
- Pedro Tavarez Jr. as "Press Photographer"
- Vincent Tumeo as "DA - Amanda's Superior"